One of your very best interviews! For you and Jim's interpretation and speaking as a reasonably well educated individual with a positive bias toward Engineering, and a small philanthropic funder of same (let me catch my breath) I want to say that my own takeaways from this interview can be distilled to appreciation of the enormity of the challenges met by a brilliant group of scientists and engineers. The brilliance of the insight that it was necessary to crack the black box problem and get at the rationales employed and to bring in and repurpose Alphafold. What a model of scientific advancement! To me the idea of circling back and revisiting and repurposing old technologies and ideas is so potentially fruitful in so many areas. Now I'll stop- it's time for me to circle back and re-read this article again!
Thanks Michael. I agree wholeheartedly with your central point on explainability. I was surprised to learn they actually used AlphaGo, the Deep Mind game precedent with the infamous Move #37!
One of your very best interviews! For you and Jim's interpretation and speaking as a reasonably well educated individual with a positive bias toward Engineering, and a small philanthropic funder of same (let me catch my breath) I want to say that my own takeaways from this interview can be distilled to appreciation of the enormity of the challenges met by a brilliant group of scientists and engineers. The brilliance of the insight that it was necessary to crack the black box problem and get at the rationales employed and to bring in and repurpose Alphafold. What a model of scientific advancement! To me the idea of circling back and revisiting and repurposing old technologies and ideas is so potentially fruitful in so many areas. Now I'll stop- it's time for me to circle back and re-read this article again!
Thanks Michael. I agree wholeheartedly with your central point on explainability. I was surprised to learn they actually used AlphaGo, the Deep Mind game precedent with the infamous Move #37!
Oops, I misspoke I meant AlphaGo of course! 😚
This is an excellent case study which illustrates and actually lets you visualize the dramatic advances (and challenges) in AI-driven drug design.