Fascinating study. To be useful in primary care discussions, these associations would be best reported as absolute and relative risks, and further explored with millions of patients before necessarily "trusting" the results reported in this paper. However, from my own "deep learning" I do find that patients' RBC indices are usually quite stable and personally unique over the years/now decades seeing them reported. I usually don't find much additional value from them unless associated with anemia, smoking, metabolic syndrome/inflammation, B12 deficiency, infection, etc. I hope this gets fleshed out and becomes more robust, thanks for sharing.
Do you have any intuitive favorite indices in cardiology considerations? Platelets as APRs come to mind...
One thing that I don't understand, and I cannot find the answer - does the direction of the move matter as much as just moving outside of the setpoint?
Fascinating study. To be useful in primary care discussions, these associations would be best reported as absolute and relative risks, and further explored with millions of patients before necessarily "trusting" the results reported in this paper. However, from my own "deep learning" I do find that patients' RBC indices are usually quite stable and personally unique over the years/now decades seeing them reported. I usually don't find much additional value from them unless associated with anemia, smoking, metabolic syndrome/inflammation, B12 deficiency, infection, etc. I hope this gets fleshed out and becomes more robust, thanks for sharing.
Do you have any intuitive favorite indices in cardiology considerations? Platelets as APRs come to mind...
One thing that I don't understand, and I cannot find the answer - does the direction of the move matter as much as just moving outside of the setpoint?
Brilliant analysis: please share the exact references cited in the article Eric 🙏
Very interesting data